Biologists captured highly transient interactions between transcription factors — proteins that control gene expression — and target genes in the genome and showed that these typically missed interactions have important practical implications. The researchers developed a method to capture transient interactions of NLP7, a master transcription factor involved in nitrogen use in plants, revealing that the majority of a plant’s response to nitrogen is controlled by these short-lived regulatory interactions.
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Biodiversity Biologists capture fleeting interactions between regulatory proteins and their genome-wide targets
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