Source: ScienceDaily
Tropane alkaloids (TAs) are heterocyclic nitrogenous metabolites found across seven orders of angiosperms, including Malpighiales (Erythroxylaceae) and Solanales (Solanaceae). Despite the well-established euphorigenic properties of Erythroxylaceae TAs like cocaine, their biosynthetic pathway remains incomplete. Using yeast as a screening platform, an international research team identified and characterized the missing steps of TA biosynthesis in Erythroxylum coca.
https://www.sciencedaily.com/releases/2022/11/221121213656.htm